Big 12 football picks and spreads for Week 7. The schedule is capped off with a primetime showdown between TCU and Iowa State. The Horned Frogs are still undefeated after a close call against Kansas State last week. The Cyclones were throttled last Saturday by Texas Tech and will now have to face Trevone Boykin. Can the home crowd help Iowa State upset TCU, or will Gary Patterson’s team continue its path to the College Football Playoff? Scroll down for this week’s Big 12 picks.

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Baylor vs. West Virginia

Date: Saturday, October 17

Kickoff: 12:00 p.m. ET

Venue: McLane Stadium

This one has the potential to be a track meet. West Virginia will put up significant points, and keep it close in the first half, but Baylor will be like Usain Bolt and completely run away with the victory. 

Pick: Baylor

Spread: Baylor -21.5

For final score prediction, check out our Baylor vs. West Virginia game preview.

Texas Tech vs. Kansas

Date: Saturday, October 17

Kickoff: 12:00 p.m. ET

Venue: Memorial Stadium

Kansas on a great day wouldn’t be able to keep up, or slow down, Texas Tech. Just like Baylor with WVU, the Red Raiders will run away – far away – from the Jayhawks.

Pick: Texas Tech

Spread: Texas Tech -31.5

For final score prediction, check out our Texas Tech vs. Kansas game preview.

Oklahoma vs. Kansas State

Date: Saturday, October 17

Kickoff: 3:30 p.m. ET

Venue: Bill Snyder Family Stadium

Oklahoma will need to dig deep this week against Kansas State. The Sooners weren’t supposed to lose to the Longhorns, and they’re definitely not supposed to lose to the Wildcats. They won’t. Baker Mayfield will have a good day and the defense do just enough.

Pick: Oklahoma

Spread: Oklahoma -4

For final score prediction, check out our Oklahoma vs. Kansas State game preview.

TCU vs. Iowa State

Date: Saturday, October 17

Kickoff: 7:00 p.m. ET

Venue: Jack Trice Stadium

Iowa State will make a game of this for most of the 60 minutes, but Trevone Boykin and the TCU offense will pull away late for a win that appears more lopsided than it was.

Pick: TCU

Spread: TCU -20.5

For final score prediction, check out our TCU vs. Iowa State game preview.